Adenosine · Hua-Ming Huang
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written by Hua-Ming Huang
January 25, 2026 1 minute read
adenosine

= 腺苷


  • is a key molecule / neurotransmitter that builds up in your brain during wakefulness and triggers/induces sleepiness.
  • is a byproduct of cellular energy use, accumulates in the brain throughout the day, promoting one’s need to sleep as levels rise.

Higher adenosine levels correlate with a stronger feeling of sleepiness, also known as Sleep Drive or Sleep Pressure.


  • While you are awake, adenosine levels gradually rise, making you feel more tired.
    • Adenosine → APT (“Energy Currency”)
  • When you are asleep, adenosine is cleared away, reducing sleep pressure.
    • APT → Adenosine
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